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Studies on the relationships between biotin and the behaviour of B and T lymphocytes in the guinea-pig
Authors:F Petrelli  P Moretti  G Campanati
Institution:(1) Institute of General Physiology, University of Camerino, I-62032 Camerino, (Italy);(2) Institute of Pathological Anatomy and Histology, University of Ancona, I-62100 Ancona, (Italy)
Abstract:Summary In biotin-deficient guinea-pigs the number of circulating neutrophils is increased; lymphocytes carrying B and T markers are decreased. Incubation with biotin increases significantly the number of lymphocytes carrying B and T markers, from biotin-deficient guinea-pigs; no increase was observed when the lymphocytes from normal guinea-pigs were incubated.
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