Depression of spontaneous and ionophore-induced neurotransmitter release bySalmonella |
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| Authors: | R J Person |
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| Institution: | (1) Department of Physiology and Biophysics, The University of Oklahoma Health Sciences Center, P.O. Box 26901, 73190 Oklahoma City, OK |
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| Abstract: | Summary Exposure of frog neuromuscular junctions to heat-killed, lyophilizedSalmonella typhimurium (SR 11) produces an early increase in spontaneous transmitter release followed by depression of release and blockade of the obligatory release usually induced by ionophore X537A.This study was supported by the Office of Naval Research, Biophysics Section, NR 202-160, N00014-77-C-0630. X537A was a gift of Hoffman-LaRoche. I am greatly indebted to Dr R. McCallum for preparing the Salmonella material. J.A. Kuhn provided the technical assistance. |
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