Effect of retinoic acid on liver transglutaminase activity and carbon tetrachloride-induced liver damage in mice. |
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| Authors: | H Kohno Y Hoshino S Katoh Y Ohkubo |
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| Affiliation: | Department of Radiopharmacy, Tohoku College of Pharmacy, Sendai, Japan. |
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| Abstract: | Transglutaminase (TGase) activity in the cytosol fraction of the mouse liver increased following intraperitoneal injection of retinoic acid. Retinoic acid inhibited the carbon tetrachloride-induced increase in serum alanine transaminase activity. These findings suggest that TGase is involved in the effect of retinoic acid on carbon tetrachloride-induced liver damage. |
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