Prednisolon-Na-succinat und die Phagozytose der Leukozyten

Summary Intravenous administration of 3 mg/kg body weight prednisolon-Na-succinate (P) decreased, after 24 h, by 30% the bacterial phagocytosis of leukocytes of rabbits. After 48 h, the effect became a slight increase. At a dosis of 0.3 mg/kg, P exerts a stimulating effect which ceases within some hours. Inin vitro experiments, it showed increased or decreased action depending upon the concentration. When perfused through the liver, the efficacy of P rises strikingly.