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法莫替丁对鼠胃肠肌电活动的影响
引用本文:陈天华,秦晓民.法莫替丁对鼠胃肠肌电活动的影响[J].甘肃科学学报,1997,9(4):59-61.
作者姓名:陈天华  秦晓民
作者单位:兰州医学院物理教研室,兰州医学院生理教研室
基金项目:甘肃省教委自然科学基金
摘    要:观察12只大鼠法莫替丁对体胃肠肌电活动的影响,结果发现:腹腔注射法莫替丁5min左右胃窦肌电活动开始增强,40min慢皮和快波振幅明显增大;十二指肠电活动除快经有所提高外,漫波频率、慢波和快波振幅均未见明显改变。提示法莫替丁可兴奋胃窦肌电活动

关 键 词:法莫替丁      电活动  胃动力药物

THE EFFECTS OF FAMOTIDINE ON GASTROINTESTINAL MYOELECTRIC ACTIVITY IN RATS
Chen Tianhua.THE EFFECTS OF FAMOTIDINE ON GASTROINTESTINAL MYOELECTRIC ACTIVITY IN RATS[J].Journal of Gansu Sciences,1997,9(4):59-61.
Authors:Chen Tianhua
Abstract:The effects of famotidine on gastrointestinal myoelectric activity were investigated in vivo in 12 rats.At 5 min after injection of famotidine,antral myoelectric activity began increasing;at about 40 min,the amplitdues of slow wave and fast wave increased significantly( P < 0.05 ),while the frequency of slow wave and the amplitude of slow wave and fast wave had no significant change except the enhancement of the percentage of fast wave containing spike bursts of duodenum.The conclusion is famotidine could excite antral myoelectric activity.
Keywords:famotidine  gastrointestinal myoelectric activity  in vivo
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