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Isolation of a potent allergen from house dust mite by interaction with the lectin tridacnin
Authors:B. A. Baldo  K. J. Turner  G. Uhlenbruck
Affiliation:(1) Clinical Immunology Unit, Princess Margaret Hospital, University of Western Australia, 6008 Subiaco, W. Australia;(2) Present address: Department of Immunobiology, Medical University Clinic, D-5 Köln-Lindenthal, German Federal Republic, BRD
Abstract:Summary Tridacnin, the lectin from the clamTridacna maxima, precipitates with house dust mite extracts and provides a simple procedure for obtaining a potent, purified mite allergen. Allergenic activity was investigated using the radioallergosorbent test (RAST).We thankKarin Williams, Jill Butler, Elizabeth Quinn andGisela Steinhausen for technical help. This work was supported by the Princess Margaret Children's Medical Research Foundation, the Asthma Foundation of Western Australia, the National Health and Medical Research Council and the Deutsche Forschungsgemeinschaft.
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