| Applying generalized hydrophobicity scale of amino acids to quantitative prediction of human leukocyte antigen-A^＊0201-restricted cytotoxic T lymphocyte epitope |
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| 作者姓名： | ZHOU Peng TIAN Feifei ZHANG Mengjun LI Zhiliang |
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| 作者单位： | [1]College of Chemistry and Chemical Engineering, Chongqing University, Chongqing 400044, China [2]State Key Laboratory of Chemo/Biosensing and Chemometdcs, Changsha 410082, China [3]Department of Medical Analysis, Third Surgeon University, Chongqing 400044, China |
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| 摘 要： | Human major histocompatibility complex (MHC), the so-called human leukocyte antigen (HLA), is usu- ally divided into three classes. Class ? protein is en- coded by three general genetic loci, HLA-A, HLA-B and HLA-C. In class ? HLA, the allele of 0201 type…
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| 关 键 词： | 疏水性 氨基酸 CTL抗原决定基 遗传算法 白细胞抗原 T淋巴细胞 |
| 收稿时间： | 2005-12-05 |
| 修稿时间： | 2005-12-052006-03-21 |
Applying generalized hydrophobicity scale of amino acids to quantitative prediction of human leukocyte antigen-A*0201-restricted cytotoxic T lymphocyte epitope |
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| ZHOU Peng TIAN Feifei ZHANG Mengjun LI Zhiliang.Applying generalized hydrophobicity scale of amino acids to quantitative prediction of human leukocyte antigen-A*0201-restricted cytotoxic T lymphocyte epitope[J].Chinese Science Bulletin,2006,51(12):1439-1443. |
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| Authors: | Peng Zhou Feifei Tian Mengjun Zhang Zhiliang Li |
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| Institution: | (1) College of Chemistry and Chemical Engineering, Chongqing University, Chongqing, 400044, China;(2) State Key Laboratory of Chemo/Biosensing and Chemometrics, Changsha, 410082, China;(3) Department of Medical Analysis, Third Surgeon University, Chongqing, 400044, China |
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| Abstract: | |
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| Keywords: | generalized hydrophobicity scale of amino acids HLA-A*0201 CTL epitope quantitative structure-activity relation- ship genetic algorithm-partial least square regression |
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