| Abstract: | Use of fundo-antral gastric transplants excised from Rat or guinea-pig stomach in order to repair fundo-antral fistula was well tolerated by adult Rats and compatible with a normal survival. In 90% of homologous transplantation, and 70% of heterologous transplantation, no brutal and mortal rejection of transplant was observed. The transplant did not regenerate, but its corpse was not eliminated, and remained united to the wall of the receiver's stomach, and infiltrated with lymphocytes. We explain the benignity of immunologic reaction in evoking the role of the liver which acts as a filter in sequestering a great part of antigens, and so moderating the antibody response by the spleen and lymphoid system. |
