Thiamine transport by human intestine in vitro |
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Authors: | G Rindi G Ferrari |
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Institution: | (1) Institute of Human Physiology, University of Pavia, via Forlanini 6, I-27100 Pavia, (Italy) |
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Abstract: | Summary Surgical specimens of human gastrointestinal mucosa and muscle were incubated in vitro with thiaminethiazole-2-14C. Labelled thiamine uptake was uphill in mucosal tissues and downhill in muscle. Small intestinal mucosa accumulated labelled thiamine in a phosphorylated form, while gastric and colonic mucosa, as well as muscular layers of all gastrointestinal segments studied, did not.This work was supported in part by a grant from the Italian Research Council, Rome, Italy. |
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