Effect of heat-labile enterotoxin (LT) produced byEscherichia coli on in vitro cell proliferation |
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| Authors: | A Pessina Maria Grazia Neri A Muschiato |
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| Institution: | (1) Department of Microbiology, Faculty of Medicine, University of Milan, 31, Mangiagalli, I-20133 Milan, (Italy);(2) Department of Pathology, Hospital of Desio, Desio, I-20033 Milan, (Italy) |
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| Abstract: | Summary Filtrates fromE. coli H10407 cultures, giving a positive response for heat-labile enterotoxin (LT) in the Y-1 cell test, show an inhibitory activity both on3H-thymidine uptake by Ehrlich ascites cells and on granulocytic-macrophagic precursors (CFU-C) in murine bone marrow.Acknowledgments. We gratefully acknowledge the expert technical assistance of L. Basso and A. Gerosa of Department of Pathology, Hospital of Desio. |
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