Effects of kallidinogenase on urinary kallikrein excretion and plasma prostanoid concentrations in patients with essential hypertension期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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Effects of kallidinogenase on urinary kallikrein excretion and plasma prostanoid concentrations in patients with essential hypertension

Authors:	K Ogawa T Ito M Ban M Motizuki T Satake

Institution:	(1) The 2nd Department of Internal Medicine, Nagoya University School of Medicine, 65 Tsuruma-cho, Showa-ku, 466 Nagoya, (Japan)

Abstract:	Summary The effects of kallidinogenase on urinary kallikrein excretion, plasma immunoreactive prostanoids and platelet aggregation were investigated in patients with essential hypertension. Urinary kallikrein excretion and plasma 6-keto PGF₁ concentration were significantly decreased in these patients. Significant decreases in blood pressure, as well as significant increases of urinary kallikrein excretion and plasma 6-keto PGF₁ concentration after kallidinogenase administration were also observed.

Keywords:	Kallidinogenase kallikrein 6-keto PGF₁" target="_blank">gif" alt="agr" align="BASELINE" BORDER="0"> thromboxane B₂ platelet aggregation essential hypertension
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