The sedative effects of nicotinamide on gerbil wheel-running activity |
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Authors: | J M Beaton |
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Institution: | (1) Neurosciences Program and Department of Psychiatry, University of Alabama Medical Center, University Station, 35294 Birmingham, Alabama, USA |
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Abstract: | Summary The activity of 5 groups of gerbils was monitored over 22 days. 3 of the groups received daily injections of nicotinamide (125, 250 or 500 mg/kg) and a 4th group received saline. The 5th group was untreated. The results indicated that both the 250 and 500 mg/kg nicotinamide administrations greatly reduced the activity levels of the gerbils.This work was supported in part by Faculty Research Grant No. 82-6209 from the University of Alabama in Birmingham to J.M.B. |
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