Demonstration of vitamin D3 metabolism inmytilus edulis |
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Authors: | I. Lehtovaara T. Koskinen |
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Affiliation: | (1) Department of Clinical Sciences, University of Tampere, Teiskontie 35, SF-33520 Tampere, (Finland) |
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Abstract: | Summary Radiolabeled vitamin D3 was converted into several polar metabolites upon incubation with tissue homogenates from the common musselMytilus edulis. Chromatographic analysis indicated that the metabolites have chromatographic mobilities different from those of known standards. The results suggest that vitamin D3 is metabolized in mussels via pathways that differ from the vertebrate systems.Acknowledgments. The authors thank Dr Pirjo Rantamäki for the mussels and F. Hoffmann-La Roche & Co. for supplying the vitamin D3 metabolite standards. This work was supported by a grant from the Magnus Ehrnrooth Foundation to T. K. |
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Keywords: | Vitamin D3 metabolism marine mussel chromatographic analysis |
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