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Enhancement of the cytogenetic efficacy of the antitumor agent bleomycin by the calcium and calmodulin antagonist fendiline |
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| Authors: | W. Scheid H. Traut |
| Affiliation: | (1) Institut für Strahlenbiologie, Universität Münster, D-4400 Münster, (Federal Republic of Germany) |
| Abstract: | Summary The induction of chromosome aberrations (dicentric and ring chromosomes) in human lymphocytes by the antitumor agent bleomycin is synergistically enhanced when bleomycin is applied together with the calcium antagonist fendiline (Sensit®). |
| Keywords: | Bleomycin calcium antagonist calmodulin antagonist chromosome aberrations comutagenesis cytostatics fendiline lymphocytes verapamil |
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