| 不依赖特异性抗体激活补体经典途径的机理探讨 |
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| 引用本文： | 黄秀琴,陈冬梅.不依赖特异性抗体激活补体经典途径的机理探讨[J].华东师范大学学报(自然科学版),1995(3):89-92. |
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| 作者姓名： | 黄秀琴 陈冬梅 |
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| 作者单位： | 华东师范大学生物学系 |
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| 摘 要： | 实验证实了Ｅ．ｃｏｌｉＢ和Ｅ．ｃｏｌｉｋ１２ ｇａｌ＾＋的细胞壁可直接激活补本，去壁扣的细菌球形体或原生质体加入补体后可裂解，说明在不依赖特异抗体激活补体经典途径中，补体的激活部位是细胞壁，作用靶子似乎是细胞膜。
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| 关 键 词： | 经典途径 原生质体 细胞壁 抗体 补体 激活 |
A Study on Mechanism of the New Complement Activation Pathway of some Bacteria |
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| Huang Xinqin,Chen Dongmei,Ni Xiaohua.A Study on Mechanism of the New Complement Activation Pathway of some Bacteria[J].Journal of East China Normal University(Natural Science),1995(3):89-92. |
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| Authors: | Huang Xinqin Chen Dongmei Ni Xiaohua |
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| Abstract: | Evidence was presented that the new complement activation pathway of some Bacteria was closely related cell wall by inhibition of haemolytic activity. However, some spheroplast or protoplast can be rapidly killed by serum in the presence of lysozyme, although these Bacteria were resistant to killed by serum in the absence of lysozyme. It seems more likely that the primary site of action of complement is at the bacteria cell wall, the lethal event was subsequent damage to the bacteria cell membrane. |
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| Keywords: | classical pathway spheroplast protoplast cell wall cell membrane |
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