Hormonal regulation of a new female-specific serum protein (FP) of the laboratory rat |
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| Authors: | R Schade W Bürger |
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| Institution: | (1) Institut für Pharmakologie und Toxikologie, Abteilung Toxikologie, Humboldt-Universität zu Berlin, Bereich Medizin (Charité), Clara-Zetkin-Strasse 94, DDR-108 Berlin, (German Democratic Republic);(2) Abteilung Klinische Immunologie, Humboldt-Universität zu Berlin, Bereich Medizin (Charité), Ziegelstrasse, DDR-108 Berlin, (German Democratic Republic) |
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| Abstract: | Summary This paper reports evidence for a hormonal regulation of a new rat serum protein (female specific protein, FP) which is only demonstrable in female rats. Male and female rats were treated with testosterone and estrogen. The FP was assayed with immunological methods. The following results were obtained: 1. In testosterone-treated females the serum level of FP is reduced significantly. 2. In estrogenized males the FP was distinctly demonstrable but not in the control males. |
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