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小腰大边型封堵器堵闭膜部瘤室间隔缺损68例观察
引用本文:高虹,董少红,张智伟,罗林杰,石继军,陈科奇,王树水,李俊杰.小腰大边型封堵器堵闭膜部瘤室间隔缺损68例观察[J].暨南大学学报,2009,30(6).
作者姓名:高虹  董少红  张智伟  罗林杰  石继军  陈科奇  王树水  李俊杰
作者单位:1. 暨南大学附属第二医院深圳市人民医院,心内科,广东,深圳,518020
2. 广东省人民医院心血管病研究所,广东,广州,510100
基金项目:国家"十五"科技攻关计划项目 
摘    要:目的:探讨小腰大边封堵器堵闭室间隔膜部瘤缺损(PPVS)的不同部位的疗效及并发症.方法:对68例室间隔缺损(VSD)伴膜部瘤患者进行小腰大边封堵器介入治疗,术中左室造影,根据瘤体形态分为4种类型,选择4~14 mm封堵器选择不同部位进行封堵.术后24 h、1个月、3个月、6个月、12个月予以胸片、心电图、经胸超声心动图检查.结果:本组68例采用细腰大边封堵器进行封堵室间隔缺损(VSD)的患儿中,62例成功(91%).术后24 h复查超声心动图,8例少量残余分流.术后1年复查残余分流消失.9例传导阻滞患者心电图3个月内均恢复正常.结论:小腰大边封堵PPVS是安全和可行的方法,并发症少,但需正确判断膜部瘤的大小、形态、位置及瓣膜功能.

关 键 词:室间隔缺损  膜部瘤  介入治疗  堵闭器

Clinical observation of interventional therapy of using thin-waist-big-side occluder to 68 cases of perimembranous ventricular septal defect with aneurysm
GAO Hong,DONG Shao-hong,ZHANG Zhi-wei,LUO Lin-jie,SHI Ji-jun,CHEN Ke-qi,WANG Shu-shui,LI Jun-jie.Clinical observation of interventional therapy of using thin-waist-big-side occluder to 68 cases of perimembranous ventricular septal defect with aneurysm[J].Journal of Jinan University(Natural Science & Medicine Edition),2009,30(6).
Authors:GAO Hong  DONG Shao-hong  ZHANG Zhi-wei  LUO Lin-jie  SHI Ji-jun  CHEN Ke-qi  WANG Shu-shui  LI Jun-jie
Abstract:Aim:There are some limitations on closure of perimembranous ventricular septal defect with pseudoaneurysm (PPVS) with symmetrical and non-decenter type oceluders. This study try to evalu-ate the effectiveness and complications of interventional therapy using A4B2 (thin-waist-big-side type)occluder to PPVS. Methods: The ventricular septal defects with aneurysems were classified into four types and measured by left ventriculography. The diameter of the occludem ranged from 4 to 14 mm.TTE, chest X-ray film and electrocardiogram (ECG) were performed 1,3,6 and 12 months later to evalu-ate the efficacy. Results: Among the 68 patients, transcatheter closures were successfully conducted to 62 patients, the success rate was 91%. Residual shunt was found by transthroacic echocardiograohy (TTE) in 8 patients 24 hours later and disappeared in 12 months. Transient block in 9 patients disap-peared 3 months later. Conclusion: Interventional therapy with A_4B_2 occluder to perimembranous ven-tricular septal defect with pseudoaneurysm is safe,effective and promising,and has fewer complications.The key point is to select the suitable positions and right occluder,according to the size,position,mor-phologic characters and valve function.
Keywords:ventricular septal defect  membranous aneurysm  occluder  interventional therapy
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