Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit |
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| Authors: | S. B. Kandasamy |
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| Affiliation: | (1) Department of Pharmacology, School of Pharmacy, University of Benin, Benin City, (Nigeria) |
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| Abstract: | Summary Hyperthermia induced by arachidonic acid in rabbit was attenuated by phenoxybenzamine, cyproheptadine and indomethacin. The reduction in arachidonic acid hyperthermia, after 6-OH-DA and the failure of PCPA to reduce this rise, indicates the involvement of noradrenaline in arachidonic acid hyperthermia. |
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