| 薄层层析—紫外分光光度法测定APC药片中三组分的含量 |
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| 引用本文： | 张秋萍,吴立城.薄层层析—紫外分光光度法测定APC药片中三组分的含量[J].湘潭大学自然科学学报,1993,15(2):94-97. |
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| 作者姓名： | 张秋萍 吴立城 |
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| 作者单位： | 湘潭大学化学系
(张秋萍，吴立城)，湘潭大学化学系(林富饮) |
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| 摘 要： | APC称复方阿斯匹林,又称复方乙酰水杨酸,是最常用的热镇痛药。其组分是阿斯匹林、非那西丁、咖啡因。对APC含量分析一般采用容量法,此法操作繁琐,有文献报道采用液相色谱法和薄层色谱法,而对APC某一成分用光度法测定也有报道。本文采用薄层层析法和紫外分光光度法,对APC中的三组分进行分离和定量分析,取得了满意的结果。这种测定方法,尚未见报道。操作简便,仪器普及,便于推广。
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| 关 键 词： | 薄层层析 紫外分光光度 乙酰水杨酸 |
DETERMINATION OF APC TABLETS BY THIN LAYER CHROMATOGRAPHY-ULTRAVIOLET SPECTROPHOTOMETRY |
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| Zhang Qiuping Wu licheng Lin Fuqin.DETERMINATION OF APC TABLETS BY THIN LAYER CHROMATOGRAPHY-ULTRAVIOLET SPECTROPHOTOMETRY[J].Natural Science Journal of Xiangtan University,1993,15(2):94-97. |
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| Authors: | Zhang Qiuping Wu licheng Lin Fuqin |
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| Institution: | Departmeant of Chemistry |
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| Abstract: | A method of separation and determination of three compo-nents in the APC by thin-layer chromatography and ultraviolet spectropho-tometry is described.These components are separated on a silica gelGF 254 plate with benzene-ether-acetic acid-methanol(100-50-15-1)asthe developer. The absorbances of aspirin,phenacetin and caffeine aremeasured at 230nm,250nm,272nm,respectively,in UV-265. Results ofdetermination were quite satisfactory. |
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| Keywords: | thin-layer chromatography ultraviolet spectrophotometry aspirin phenacetin caffeine |
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