| 3-羟基溴代吲哚衍生物的合成研究 |
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| 引用本文： | 王国峰,冯丽恒,郭炜.3-羟基溴代吲哚衍生物的合成研究[J].山西大学学报(自然科学版),2011,34(1):106-109. |
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| 作者姓名： | 王国峰 冯丽恒 郭炜 |
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| 作者单位： | 山西大学,化学化工学院,山西,太原,030006 |
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| 基金项目： | 国家自然科学基金(20772073;20802042) |
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| 摘 要： | 通过多步合成得到4个具有潜在抗肿瘤活性及解热镇痛、阻胺作用的吲哚类医药化合物.并通过IR、1H NMR、MS和元素分析对化合物结构进行了表征.
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| 关 键 词： | 溴代吲哚 药物中间体 药物合成 |
Synthesis of 3-Hydroxyl-bromo Indoles Derivatives |
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| WANG Guo-feng,FENG Li-heng,GUO Wei.Synthesis of 3-Hydroxyl-bromo Indoles Derivatives[J].Journal of Shanxi University (Natural Science Edition),2011,34(1):106-109. |
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| Authors: | WANG Guo-feng FENG Li-heng GUO Wei |
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| Institution: | WANG Guo-feng,FENG Li-heng,GUO Wei(School of Chemistry and Chemical Engineering,Shanxi University,Taiyuan 030006,China) |
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| Abstract: | Indole and it's derivates,being one of the important fine chemical products,play important role in industry and medicine areas.Four 3-hydroxyl-bromo indole derivatives which used to antitumor activite,antipyretic analgesics and hindered amine were synthesized through many steps.These compounds were characterized by IR,1H NMR,MS and elemental analysis. |
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| Keywords: | bromination indoles drug intermediates pharmaceutical synthesis |
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