Cytostatic activity of organic compounds and their average quasi-valence number |
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| Authors: | Veljković V. Ajdačić V. |
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| Affiliation: | (1) Boris Kidri!["ccaron"]("/content/r2635g7501276628/xlarge269.gif") Institute, P. O. Box 522, 1101 Beograd, (Yugoslavia) |
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| Abstract: | Summary It is found that the average quasi-valence numbers of alkylating cytostatics lie in the region of potential carcinogens, while the average quasi-valence numbers of antimetabolites predominantly cover the region of noncarcinogens. Implications of this finding on the design of new drugs are discussed. |
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