Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats |
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Authors: | Kathie L Olsen R E Whalen |
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Institution: | (1) Long Island Research Institute, Health Sciences Center, 10T, State University of New York at Stony Brook, 11794 Stony Brook, New York, USA |
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Abstract: | Summary Androgen-insensitive (tfm) rats possess a nuclear-estrogen binding system in the brain that is similar to that of wild-type control males. In these mutant rats, radiolabeled estradiol was bound predominantly to hypothalamic nuclei and this binding was of limited capacity.This research was supported by grants Nos HD-13957 and HD-14726 from the National Institute of Child Health and Human Development. |
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