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Estrogen binds to hypothalamic nuclei of androgen-insensitive (tfm) rats
Authors:Kathie L Olsen  R E Whalen
Institution:(1) Long Island Research Institute, Health Sciences Center, 10T, State University of New York at Stony Brook, 11794 Stony Brook, New York, USA
Abstract:Summary Androgen-insensitive (tfm) rats possess a nuclear-estrogen binding system in the brain that is similar to that of wild-type control males. In these mutant rats, radiolabeled estradiol was bound predominantly to hypothalamic nuclei and this binding was of limited capacity.This research was supported by grants Nos HD-13957 and HD-14726 from the National Institute of Child Health and Human Development.
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