| L-色氨酸衍生的手性相转移催化剂的合成及其不对称诱导效应 |
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| 引用本文： | 薛爱英,刘文陆,李培刚,矫桂丽,常学顺,邹志琛.L-色氨酸衍生的手性相转移催化剂的合成及其不对称诱导效应[J].山东师范大学学报(自然科学版),2005,20(1):36-39. |
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| 作者姓名： | 薛爱英 刘文陆 李培刚 矫桂丽 常学顺 邹志琛 |
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| 作者单位： | 1. 山东师范大学化学化工与材料科学学院,250014,济南
2. 济南市历城区第三职业中专,250037,济南 |
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| 基金项目： | 山东省科技厅计划项目资助 (K10 80 3 5 ) |
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| 摘 要： | 以L-(-)-色氨酸为原料，经酯化、季铵化合成了4种手性季铵盐，以L-色氨酸甲酯为原料，经还原、季铵化合成了2种手性季铵盐；6种手性季铵盐对苯甲醛与氯仿的亲核加成反应。显示出良好的相转移催化作用和一定的不对称诱导效应。
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| 关 键 词： | 手性相转移催化剂 手性季铵盐 L-（-）-色氨酸 不对称合成 不对称诱导效应 |
SYNTHESIS AND ASYMMETRIC INTRODUCTION OF CHIRAL PHASE TRANSFER CATALYSIS DERIVED FROML- TRYPTOPHAN |
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| Xue Aiying,Liu Wenlu,Li Peigang,Jiao Guili,Chang Xueshun,Zou Zhichen.SYNTHESIS AND ASYMMETRIC INTRODUCTION OF CHIRAL PHASE TRANSFER CATALYSIS DERIVED FROML- TRYPTOPHAN[J].Journal of Shandong Normal University(Natural Science),2005,20(1):36-39. |
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| Authors: | Xue Aiying Liu Wenlu Li Peigang Jiao Guili Chang Xueshun Zou Zhichen |
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| Institution: | Xue Aiying 1) Liu Wenlu 1) Li Peigang 1) Jiao Guili 1 ) Chang Xueshun 2) Zou Zhichen 1*) |
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| Abstract: | Four kinds of chiral quaternary ammuonium salts are sy nt hesized through the ways of esteration and quaterization with L-tryptophan a s ma terials,and two kinds of the salts are synthesized via reduction and quaterariz a tion with L-tryptophan methyl ester as material.The synthsized six kinds of quat ernary ammo nium salts show good phase transfer catalysis and certain effcet of asymmetric i nduction in nucleophilic addition of benzaldehyde with chloroform. |
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| Keywords: | chiral phase transfer catalyst chiral quatermary ammu onium salt L-tryptophan asymmetric synthesis the effect of asymmetric indu ction |
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