| 骨髓间充质干细胞对放射性胸腺损伤的修复作用 |
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| 引用本文： | 王洪艳,龚守良,齐亚莉,陈玉丙.骨髓间充质干细胞对放射性胸腺损伤的修复作用[J].北华大学学报(自然科学版),2011(3):300-303. |
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| 作者姓名： | 王洪艳 龚守良 齐亚莉 陈玉丙 |
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| 作者单位： | 吉林大学公共卫生学院卫生部放射生物学重点实验室;北华大学公共卫生学院;吉林大学第二医院; |
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| 摘 要： | 目的 观察骨髓间充质干细胞(MSCs)对放射性胸腺损伤的修复作用.方法 C57BL/6小鼠行1.75Gy X 线全身照射,每周1次,连续4周.实验设正常对照组、照射组及照射+MSCs组,于末次照射后30、60、90 d称量各组小鼠体质量.取胸腺组织,计算胸腺质量指数,并通过组织学观察MSCs对胸腺组织损伤的修复作用.结...
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| 关 键 词： | 骨髓间充质干细胞 电离辐射 胸腺 损伤 修复 |
Repairment Effects of Bone Marrow Mesenchymal Stem Cells on Thymus Tissue Injury Induced by Ionizing Radiation |
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| WANG Hong-yan,GONG Shou-liang,QI Ya-li,CHEN Yu-bing.Repairment Effects of Bone Marrow Mesenchymal Stem Cells on Thymus Tissue Injury Induced by Ionizing Radiation[J].Journal of Beihua University(Natural Science),2011(3):300-303. |
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| Authors: | WANG Hong-yan GONG Shou-liang QI Ya-li CHEN Yu-bing |
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| Institution: | WANG Hong-yan1,2,GONG Shou-liang1,QI Ya-li1,CHEN Yu-bing3(1.Key Laboratory of Radiobiology,Ministry of Health,School of Public Health,Jilin University,Changchun 130021,China,2.Public Health College of Beihua University,Jilin 132013,3.The Second Hospital of Jilin University,China) |
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| Abstract: | Objective To observe the repairment effects of bone marrow mesenchymal stem cells(MSCs) on thymus tissue injury induced by ionizing radiation in mice.Method The whole bodies of mice were irradiated with 1.75 Gy X-irradiation(once a week,total four weeks) and the mice were divided into normal group,irradiation group and MSCs group.Body weights of the mice were weighed and the thymus weight indices were calculated on the 30th day,60th and 90th after the irradiation.Repairment effects of MSCs on thymus were ob... |
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| Keywords: | bone marrow mesenchymal stem cells ionizing radiation thymus damage repair |
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