| 抗菌多肽的研究进展 |
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| 引用本文： | 闫娟,;江銮銮,;袁素素,;叶秀娟,;吴子斌,;吴祖建. 抗菌多肽的研究进展[J]. 武夷科学, 2014, 0(1): 168-174 |
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| 作者姓名： | 闫娟, 江銮銮, 袁素素, 叶秀娟, 吴子斌, 吴祖建 |
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| 作者单位： | [1]福建农林大学 福建省植物病毒学重点研究室,福建福州350002; [2]福建农林大学 生物农药与化学生物学教育部重点实验室,福建福州350002; [3]香港中文大学 生物医学学院,香港新界沙田999077 |
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| 基金项目： | 闽港人才合作项目（k86130001）. |
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| 摘 要： | 抗菌多肽是在生物体中具有抗菌活性的肽类物质的总称，是无数动植物天然免疫系统的重要组成部分，具有抗菌谱广、作用强且迅速、不易产生耐药等优点。抗菌多肽已经成为药物开发的研究热点。本文简要介绍抗菌多肽的分类、作用和作用机理，并对抗菌多肽的应用前景及其存在问题进行分析。
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| 关 键 词： | 抗菌多肽 分类 来源 作用机理 |
ProGress in research on antimicrobiaL peptides |
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| Affiliation: | Juan YAN, Luan-Luan JIANG, Su-Su YUAN, Xiu-Juan YE, Ng Tzibun, Zu-Jian WU ( 1. Key Laboratory of Plant Virology of Fujian Provinee, Institute of Plant Virology, Fujian Agriculture and Forestry University, Fuzhou, Fufian, 350002, China; 2. Key Laboratory of Biopesticide and Chemical Biology, Fujian Agriculture and Forestry University, Fuzhou, Fujian, 350002, China; 3. School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong 999077, China) |
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| Abstract: | AntimicrobiaL peptides（ AMPs）are generaLLy caLLed peptide exhibited antimicrobiaL activity in organism, which is an important components of the innate immune systems in pLants and animaLs,having the potentiaL of broad-spectrum activity,rapid and strong bactericidaL activity,Low propensity for resistance deveLopment and so on. At present,AMPs have become a hot topic in medicinaL deveLopment. In this paper,the cLassification,action,mecha-nism of AMPs are reviewed briefLy,and the appLication prospects and probLems are anaLyzed. |
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| Keywords: | antimicrobiaL peptides cLassification resouces mechanism |
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