Bioinformatics study indicates possible microRNA-regulated pathways in the differentiation of breast cancer |
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Authors: | YunFei Pei ZhiMin Wang Fei Fei ZhiMing Shao Wei Huang XueGong Zhang |
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Institution: | (1) Institute of Crop Science &; Institute of Bioinformatics, Zhejiang University, 310029 Hangzhou, PR China;(2) CSIRO Plant Industry, 2601 Canberra, ACT, Australia |
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Abstract: | microRNAs (miRNAs) have been reported to be associated with the pathogenesis and progression of breast cancer.However,little is known about the pathways through which miRNAs regulate these processes,e.g.,the interaction between miRNAs and their target genes with regard to different pathological status of breast cancer,such as histological grades.This study investigated the possible roles of miRNAs in the differentiation of histological grades of breast cancer with a computational approach.Based on a microar... |
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Keywords: | microRNA breast cancer TGF-&beta pathway histological grade |
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