Co-polymerization of dopa and cysteinyldopa in melanogenesis in vitro |
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| Authors: | S Ito E Novellino F Chioccara G Misuraca G Prota |
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| Institution: | (1) Institute for Comprehensive Medical Science, School of Medicine, Fujita-Gakuen University, 470-11 Toyoake, Aichi, (Japan);(2) Istituto di Biorganica, Facoltà di Farmacia, Napoli;(3) Istituto di Chimica Organica e Biologica dell'Università, Via Mezzocannone 16, I-80134 Napoli, (Italy) |
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| Abstract: | Summary Tyrosinase oxidation of dopa in the presence of varying amounts of 5-S-cysteinyldopa led to the production of pigments whose chemical and physical (colour and solubility) properties are intermediate between those of pure eumelanin-and phaeomelanin-type pigments.Acknowledgment. This work was supported in part by a grant from CNR, Rome, within the frame of the project  Controllo della crescita neoplastica . |
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