Effect of L-amino-ethyl-cysteine,a sulfur analogue of L-lysine,on virus miltiplication in mammalian cell cultures |
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| Authors: | A. Sciocia-Santoro D. Cavallini Anna M. Degener R. Perez-Bercoff G. Rita |
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| Affiliation: | (1) Institute of Biological Chemistry, University of Rome, viale di Ponte Tuburtina 28, I Rome, (Italy);(2) Institute of Virology, University of Rome, viale di Ponte Tuburtina 28, I Roma, (Italy) |
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| Abstract: | Summary L-amino-ethyl-cysteine clearly inhibits replication of Mengovirus; another RNA-virus (vesicular stomatitis virus) is completely insensitive. Protein synthesis is not impaired, but no active viral RNA-polymerase is detected.This work was partly supported by grant No. 73.01407.44 115.0107 of Consiglio Nazionale delle Ricerche, Roma, Italy. The technical collaboration of P. Meo and G. Conciatori is gratefully acknowledged. |
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