Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes |
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| Authors: | T J Jentsch K Steinmeyer G Schwarz |
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| Affiliation: | Centre for Molecular Neurobiology (ZMNH), Hamburg University, Germany. |
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| Abstract: | A complementary DNA encoding a voltage-gated chloride channel from Torpedo marmorata electric organ was cloned by expressing hybrid-depleted messenger RNA in Xenopus oocytes. The predicted protein has a sequence of 805 amino acids containing several putative membrane-spanning domains. Expression of the protein in Xenopus oocytes shows that it is sufficient for channel function. |
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