海洋微生物生物活性代谢物研究进展及技术问题

近年来,海洋微生物代谢物研究进展迅速。海洋微生物的代谢物种类主要有五大类,即:胺及酰胺类、吲哚生物碱类、乙酰配基类、环肽类及聚丙酸酯类。其生物活性包括:抗菌、抗肿瘤、抗微生物、抗病毒、酶及酶的抑制活性等,其中以抗肿瘤活性最为重要。在培养及鉴定海洋微生物等方面还面临许多问题。

Research advanees in bioactive metabolites from marine microorganisms

In recent years, research of metabolites from marine microorganisms has become a rapidly growing field. The metabolites of marine microorganisms include: amines and amides, indole alkaloids, acetogenines, cyclic peptide and polypropionates. The main bioactivities include antibacterial, antimicrobial , antitumor, antiviral activity, enzyme and enzyme inhibition, and antitumor activity is more important. There are still some problems in culturing and identifying the marine microorganism.