Untersuchungen zur Organotropie der krebserzeugenden Wirkung des N-Nitroso-N-methyl-Harnstoffes (NMH) an Ratten |
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Authors: | C. Thomas R. Bollmann |
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Affiliation: | (1) Pathologisches Institut der Universität Bonn, Deutschland;(2) Present address: Pathologisches Institut der Universität, 78 Freiburg im Breisgau, Deutschland |
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Abstract: | Summary Methyl-nitrosourea, an unstable nitrosamide, exhibits a resorptive cancerogenic effect after shorttermed oral administration of high doses (4 times 40 mg/kg body weight). Induction time and localization of the observed tumours depend, among other things, on the dose and the pH of the cancerogen solution and on the age of animals. |
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