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Organotin complexes of pyridine-2-carbothioamide
Authors:F. E. Smith  Khoo Lian Ee
Affiliation:(1) Chemistry Department, Kenyatta University College, P.O. Box 43844, Nairobi, (Kenya);(2) School of Chemical Sciences, University Sains Malaysia, Penang, (Malaysia)
Abstract:Summary Complexes of pyridine-2-carbothioamide with diethyltin dichloride, dibenzyltin dichloride and phenyltin trichloride are described. In each case, the chelating agent is bound to the tin(IV) atom by the pyridine nitrogen and the carbothioamide sulphur, giving support to proposals that certain organotin compounds cause enzyme deactivation via the formation of tin-sulphur bonds.Acknowledgment. We thank the Tin Industry (Research and Development) Board, Kuala Lumpur, for financial support.
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