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Genomic organization of EDSV strain AA-2
Authors:Liyu Zeng  Qi Jin  Jinggang Zhang  Maoxiang Li  Hong Li  Lei Zhu  Zhen Yin  Yunde Hou
Affiliation:(1) Institute of Virology, State Key Laboratory of Molecular Virology & Genetic Engineering, Chinese Academy of Preventive Medicine, 100052 Beijing, China;(2) Institute of Military Veterinary Medicine, 130062 Changchun, China
Abstract:The genomic organization of egg drop syndrome virus strain AA-2 isolated in China is reported here. The genome was found to be 32 838 bp in length, approximately 2 kb shorter than those of the human subgenus C adenoviruses. Analysis of open reading frames indicated that the genes for major viral structural proteins (55 K, Penton base, pVI, pX, pVI, Hexon, 100 K, pVI and Fiber), as well as EP, DNA polymerase and VIa II are present in the expected locations in the genome. EDSV possesses no identifiable E3 and E4 regions and most proteins encoded by E3 and E4 regions of other adenoviruses genome were not presented in EDSV.
Keywords:EDS-76  genomic organization  sequence analysis
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