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Tetanus toxin does not affect the release of noradrenaline and taurine from rat cerebral cortex slices evoked by high K+ and Na+-free media
Authors:J. Heredero  S. S. Oja
Affiliation:(1) Department de Bioquimica, Facultad de Medicina, Universidad Autonoma de Barcelona, Barcelona, Spain;(2) Present address: Department of Biomedical Sciences, University of Tampere, Box 607, SF-33101 Tampere, Finland
Abstract:Summary Noradrenaline and taurine release from superfused rat cerebral cortex slices was stimulated by potassium ions, veratrine, ouabain and omission of sodium ions. Tetanus toxin enhanced only the ouabain-evoked calcium-dependent noradrenaline release and the ouabain-evoked calcium-independent taurine release. The uptake of both was marginally affected.
Keywords:Brain slices  noradrenaline  taurine  evoked release  uptake  tetanus toxin
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