| 孕鼠铁缺乏对仔鼠出生健康的影响 |
| |
| 引用本文： | 付锦艳,杨安强,刘旻,马雅静,程江. 孕鼠铁缺乏对仔鼠出生健康的影响[J]. 石河子大学学报(自然科学版), 2009, 27(2) |
| |
| 作者姓名： | 付锦艳 杨安强 刘旻 马雅静 程江 |
| |
| 作者单位： | 付锦艳,杨安强,刘旻,FU Jinyan,YANG Anqiang,LIU Min(新疆地方与民族高发病教育部重点实验室,石河子,832002);马雅静,程江,MA Yajing,CHEN Jiang(石河子大学医学院第一附属医院,石河子,832008) |
| |
| 摘 要： | 通过建立孕期大鼠铁缺乏的模型来研究生命早期低铁干预对仔鼠出生健康的影响.将6周龄健康Wistar 雌性大鼠随机分为二组,实验组喂低铁饲料,对照组喂富铁饲料;4周后与正常成年雄鼠合笼交配,观察母鼠受孕率和铁营养水平及仔鼠出生体重和铁营养状况.结果显示低铁组雌鼠孕末期血红蛋白值低于对照组,而红细胞数、红细胞游离原卟啉、红细胞分布宽度均高于对照组雌鼠 (P<0.05).低铁组仔鼠存活率及肝脏铁、血清铁水平均低于对照组(P<0.05).因此,大鼠孕期低铁干预不仅影响孕鼠的铁代谢,也影响仔鼠的出生健康.
|
| 关 键 词： | 孕鼠 铁缺乏 铁干预 |
Effect of Iron Deficiency in Pregnant Rat on Birth Health of Its Offspring |
| |
| FU Jinyan,YANG Anqiang,LIU Min,MA Yajing,CHEN Jiang. Effect of Iron Deficiency in Pregnant Rat on Birth Health of Its Offspring[J]. Journal of Shihezi University(Natural Science), 2009, 27(2) |
| |
| Authors: | FU Jinyan YANG Anqiang LIU Min MA Yajing CHEN Jiang |
| |
| Affiliation: | 1 Key Laboratory of Xinjiang Endemic and Ethnic Disease;Shihezi University;Shihezi 832002;China;2 The First Affiliated Hospital of Shihezi University College of Medicine;Shihezi 832008;China |
| |
| Abstract: | A nutritional iron deficient model of pregnancy rats was established to explore the life.Healthy six-month female Wistar rats were randomly divided into two groups(control group and experimental group),The rats in experimental group and control group were fed on low iron or normal diet respectively.After four weeks,the female rats were mated with healthy adult male rats to detect the maternal reproduction funtion and neonatal iron metabolism.Hemoglobin were lower in experimental group than those in control ... |
| |
| Keywords: | pregnant rat iron deficiency iron intervention |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
