Superoxide anion scavenging effect and superoxide dismutase activity ofGinkgo biloba extract期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Superoxide anion scavenging effect and superoxide dismutase activity ofGinkgo biloba extract

Authors:	J. Pincemail M. Dupuis C. Nasr P. Hans M. Haag-Berrurier R. Anton C. Deby

Affiliation:	(1) Laboratoire de Biochimie et de Radiobiologie, Institut de Chimie, Université de Liège, B6 Sart Tilman, B-4000 Liège, (Belgium);(2) Laboratoire de Pharmacognosie, Faculté de Pharmacie, Université Louis Pasteur, Route du Rhin 74, Illkirch-Graffenstaden, F-67048 Strasbourg Cedex, (France);(3) CHU, Université de Liège, B33 Sart-Tilman, B-4000 Liège, (Belgium)

Abstract:	Summary Ginkgo biloba extract is known to be efficient in diseases associated with free radical generation. The purpose of this work was to study, under in vitro conditions, the action ofGinkgo biloba extract (Gbe) against superoxide anion ( $O_{2^{bar .} }$ ), which is directly or indirectly implicated in cell damage.Gbe appears to have both an $O_{2^{bar .} }$ scavenging effect and also a superoxide dismutase activity. Its antiradical effect was demonstrated by low temperature electron spin resonance and in a non-enzymatic system (phenazine methosulfate-NADH), and its enzymatic activity was shown by polarographic determination.

Keywords:	Ginkgo biloba superoxide anion superoxide dismutase
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