Progress in artificial control system for gene expression |
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Authors: | Yong Zhang Nanming Zhao Qiang Liu |
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Affiliation: | (1) Department of Biological Science and Biotechnology, Tsinghua University, 100084 Beijing, China;(2) Department of Biological Science and Biotechnology, State Laboratory of Biomembrane and Membrane Biotechnology, Tsinghua University, 100084 Beijing, China |
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Abstract: | Along with the increasingly wide application of transgenic techniques, new stricter criteria have been raised for controlling the expression of exogenous genes. For these demands, a series of artificial control systems for gene expression have been developed and testified in recent years, which can control exogenous genes expression in exact time and certain level by administration of a specific drug or hormone. The successful construction of these systems offers a practicable method to control precise expression of exogenous gene in organisms, and raises the feasibility of wide application of gene therapy. |
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Keywords: | control system expression control exogenous gene |
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