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右美托咪啶靶控输注对老年胃肠手术患者全麻诱导期血流动力学和术后恢复的影响
引用本文:韩庆波,刘洋,郭平选,唐山开,李辛洁.右美托咪啶靶控输注对老年胃肠手术患者全麻诱导期血流动力学和术后恢复的影响[J].北华大学学报(自然科学版),2016,17(1):79-81.
作者姓名:韩庆波  刘洋  郭平选  唐山开  李辛洁
作者单位:开滦总医院,河北 唐山,063000;开滦总医院,河北 唐山,063000;开滦总医院,河北 唐山,063000;开滦总医院,河北 唐山,063000;开滦总医院,河北 唐山,063000
基金项目:河北省自然科学基金项目(H2014209272),唐山市科技发展计划项目(13130218-b)
摘    要:目的探讨靶控输注右美托咪啶对老年胃肠手术患者全麻诱导期血流动力学和术后恢复情况的影响.方法选取行胃肠手术的老年患者86例,随机分为观察组和对照组,每组各43例.观察组患者麻醉诱导前行静脉靶控输注右美托咪啶,对照组患者给予等量的生理盐水,对比两组患者血流动力学变化情况及术后恢复情况.结果观察组患者在麻醉诱导后2 min与诱导前相比收缩压、舒张压和平均动脉压水平均降低,但无统计学意义(P0.05);对照组患者在麻醉诱导后2 min与诱导前相比收缩压、舒张压和平均动脉压水平均明显降低,差异具有统计学意义(P0.05).观察组患者术后呼吸恢复时间、睁眼时间、拔管时间、镇静评分和躁动评分均明显低于对照组患者,差异具有统计学意义(P0.05).结论老年胃肠手术患者全麻诱导期靶控输注右美托咪啶能够有效稳定血流动力学表现,改善术后恢复情况.

关 键 词:右美托咪啶  胃肠手术  全麻诱导

Effects of Dexmedetomidine Target Controlled Infusion on Hemodynamics in Anesthesia Induction Period and Postoperative Recovery in Elderly Patients Accepted Gastrointestinal Surgery
Han Qingbo,Liu Yang,Guo Pingxuan,Tang Shankai,Li Xinjie.Effects of Dexmedetomidine Target Controlled Infusion on Hemodynamics in Anesthesia Induction Period and Postoperative Recovery in Elderly Patients Accepted Gastrointestinal Surgery[J].Journal of Beihua University(Natural Science),2016,17(1):79-81.
Authors:Han Qingbo  Liu Yang  Guo Pingxuan  Tang Shankai  Li Xinjie
Abstract:Objective To explore the effects of dexmedetomidine target controlled infusion on hemodynamics during anesthesia induction period and postoperative recovery in elderly patients accepted gastrointestinal surgery. Method 86 cases of elderly patients accepted gastrointestinal surgery were randomly divided into observation group and control group, with 43 cases in each group. The observation group was administrated dexmedetomidine target controlled infusion before anesthesia induction,and the control group was given the same amount of saline solution. The hemodynamics and postoperative recovery of the patients were compared between two groups. Results In the observation group,the systolic pressure,diastolic pressure and mean arterial pressure levels were lower at 2 min after anesthesia induction,but the difference was not significant (P>0. 05). In the control group, the patients ' systolic pressure, diastolic pressure and mean arterial pressure levels were significantly lower at 2 min after anesthesia induction (P<0. 05). Compared with the control group,the breathing recovery time, eye opening time, extubation time and sedation-agitation scale were obviously lower in the observation group (P<0. 05). Conclusion During the period of anesthesia induction,dexmedetomidine target controlled infusion can effectively stabilize hemodynamics performance and improve postoperative recovery in elderly patients suffered gastrointestinal surgery.
Keywords:Dexmedetomidine  gastrointestinal surgery  induction of general anesthesia
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