| 三聚磷酸钠对草酸钙晶体生长的影响及其防石机理 |
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| 引用本文： | 赵美霞,于海燕,吴秀梅,欧阳健明.三聚磷酸钠对草酸钙晶体生长的影响及其防石机理[J].暨南大学学报,2006,27(5):705-709. |
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| 作者姓名： | 赵美霞 于海燕 吴秀梅 欧阳健明 |
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| 作者单位： | 暨南大学化学系,广东,广州,510632 |
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| 基金项目： | 国家自然科学基金;国家自然科学基金;教育部留学回国人员科研启动基金 |
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| 摘 要： | 采用扫描电子显微镜(SEM)和X-射线衍射(XRD)方法研究了三聚磷酸钠对草酸钙(CaOxa)晶体生长的影响.三聚磷酸钠能抑制一水草酸钙(COM)晶体的生长,同时诱导二水草酸钙(COD)晶体的形成.随着三聚磷酸钠浓度的增加,COM晶体的表面积减少.上述结果表明三聚磷酸钠是抑制CaOxa结石的一种潜在药物.
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| 关 键 词： | 草酸钙 三聚磷酸钠 尿结石 |
| 文章编号： | 1000-9965(2006)05-0705-05 |
| 收稿时间： | 11 11 2005 12:00AM |
| 修稿时间： | 2005年11月11 |
Effect of sodium tripolyphosphate on crystallization of calcium oxalate and its mechanism on prevention of urinary stones |
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| ZHAO Mei-xia,YU Hai-yan,WU Xiu-mei,OUYANG Jian-ming.Effect of sodium tripolyphosphate on crystallization of calcium oxalate and its mechanism on prevention of urinary stones[J].Journal of Jinan University(Natural Science & Medicine Edition),2006,27(5):705-709. |
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| Authors: | ZHAO Mei-xia YU Hai-yan WU Xiu-mei OUYANG Jian-ming |
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| Institution: | Department of Chemistry, Jinan University, Guangzhou 510632, China |
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| Abstract: | The effect of sodium tripolyphosphate(Na_5P_3O_(10)) on the morphology and phase compositions of calcium oxalate(CaOxa) crystals was investigated in gel systems by a double diffusion technique using scanning electron microscopy and Fourier transform infrared(FT-IR) spectroscopy.The addition of Na_5P_3O_(10) could inhibit the growth of cal-(cium) oxalate monohydrate(COM) and induce the formation of calcium oxalate dihydrate(COD) crystals.With the increase of Na_5P_3O_(10) concentration,the surface area of COM crystals decreased and the percentage of COD crystals increased.It indicated that Na_5P_3O_(10) maybe a potential inhibitor to calcium oxalate urinary stones. |
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| Keywords: | calcium oxalate sodium tripolyphosphate urinary stone |
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