Enhancement by caffeine of the frequency of anaphase-telophase chromatin bridges induced by triethylenemelamine (TEM) |
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| Authors: | F N Dulout M L Larramendy O A Olivero |
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| Institution: | (1) Instituto Multidisciplinario de Biología Celular, CC 403 1900 La Plata, (Argentina) |
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| Abstract: | Summary Treatment of BHK cells for 8 h with triethylenemelamine (TEM) followed by caffeine for 4 or 8 h, increased the frequency of anaphase-telophase chromatin bridges in relation to controls and TEM-treated cells. These results indicate that TEM-induced chromosome lesions detected as chromatin bridges at anaphase-telophase could be potentiated by caffeine.This work was supported by grants from CIC, CONICET and CAFPTA. |
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