Changes in gastro-intestinal serotonin content associated with fasting and satiation |
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| Authors: | G Biggio M P Piccardi M L Porceddu G L Gessa |
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| Institution: | (1) Institute of Pharmacology, University of Cagliari, via Porcell 4, I-09100 Cagliari, (Italy) |
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| Abstract: | Summary Rats fasted for 24 h were fed for 3 h, after whith time food was removed. Food intake decreased serotonin levels in the stomach and duodenum by 30 and 40%, respectively. These changes persisted for about 3 h. Food intake did not change tryptophan content in the stomach, while, in the duodenum, tryptophan level rose by 100% at the end of the feeding period and remained elevated for about 9 h. |
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