| 高氯酸镁催化不对称Diels-Alder反应 |
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| 引用本文： | 金建荣,陈维一,李新生.高氯酸镁催化不对称Diels-Alder反应[J].浙江师范大学学报(自然科学版),2006,29(3):302-305. |
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| 作者姓名： | 金建荣 陈维一 李新生 |
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| 作者单位： | 1. 苏州大学,化学化工学院,江苏,苏州,215123
2. 浙江师范大学,化学与生命科学学院,浙江,金华,321004 |
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| 摘 要： | 以手性2-噁唑啉酮为手性源合成了亲双烯体,在高氯酸镁为Lew is酸催化剂的条件下,对(4S)-3-丙烯酰基-4-苄基-2-噁唑啉酮和环戊二烯的不对称D iels-A lder反应进行了初步的研究.结果表明,高氯酸镁催化体系有较好的化学催化性能和一定的立体选择能力,主产物构型为endo,主产物光学纯度可达58%.
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| 关 键 词： | 高氯酸镁 氨基酸 不对称反应 Diels-Alder反应 |
| 文章编号： | 1001-5051（2006）03-0302-04 |
| 收稿时间： | 2006-02-16 |
| 修稿时间： | 2006-04-27 |
Asymmetric Diels-Alder reaction catalyzed by Mg( ClO4 )2 |
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| JIN Jianrong,CHEN Weiyi,LI Xinsheng.Asymmetric Diels-Alder reaction catalyzed by Mg( ClO4 )2[J].Journal of Zhejiang Normal University Natural Sciences,2006,29(3):302-305. |
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| Authors: | JIN Jianrong CHEN Weiyi LI Xinsheng |
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| Institution: | 1. College of Chemistry and Chemical Engineering, Suzhou University, Suzhou Jiangsu 215123, China ;2. College of Chemistry and Life Scieacey , Zhejiang Normal Uaiversity , Jinhua Zhejiang 321004, China |
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| Abstract: | It was reported the study of asymmetric DielsAlder reaction of chiral acrylamides with cyclopentadiene in the presence of Mg(ClO_4)_2.The investigation showed that moderate diastereoselective and enantioselective carbon Diels-Alder reactions could be achieved in the presence of Mg(ClO_4)_2,under the reaction conditions,endo-adduct was obtained as the major product,and the ee of major product was up to 58%. |
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| Keywords: | Mg(ClO_4)_2 amino acid asymmetric reaction Diels-Alder reaction |
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