| 川楝素对骨骼肌、平滑肌和心肌收缩的作用 |
| |
| 引用本文： | 王德南,徐科.川楝素对骨骼肌、平滑肌和心肌收缩的作用[J].复旦学报(自然科学版),1987(2). |
| |
| 作者姓名： | 王德南 徐科 |
| |
| 作者单位： | 复旦大学遗传学研究所，中国科学院上海生理研究所 八四级博士研究生. |
| |
| 摘 要： | 川楝素能轻度可逆地增强箭毒化及去神经骨骼肌由直接刺激引起的收缩反应.当用Sr~(2+)代替溶液中的Ca~(2+)时,这种正肌力作用仍能出现.川楝素对豚鼠平滑肌的自发收缩亦有增强作用,但川楝素对大鼠心肌由直接电刺激引起的收缩反应则具有负肌力作用.
|
| 关 键 词： | 川楝素 正肌力作用 负肌力作用 |
EFFECTS OF TOOSENDANIN ON THE CONTRACTION OF SKELETAL, SMOOTH AND CARDIAC MUSCLES |
| |
| Wang Denan.EFFECTS OF TOOSENDANIN ON THE CONTRACTION OF SKELETAL, SMOOTH AND CARDIAC MUSCLES[J].Journal of Fudan University(Natural Science),1987(2). |
| |
| Authors: | Wang Denan |
| |
| Institution: | Wang Denan(Institute of Genetics Fudan University)Xu Ke(Shanghai Institute of Physiology Academia Sinica) |
| |
| Abstract: | Toosendanin enhanced slightly and reversibly the contraction response of curarized or denervated skeletal muscle to direct stimulation in rat. And this positively inotropic effect persisted when Ca~(2+) was replaced by Sr~(2+). Toosendanin also enhanced the spontaneous contraction of guinea pig's smooth muscle, but it had negtively inotropic effect on thecontraction of oardiac muscle evoked by direct stimulation in rat. |
| |
| Keywords: | toosendanin positively inotropic effect negtively inotropic effect |
| 本文献已被 CNKI 等数据库收录！ |
