Distribution of the 1,25 dihydroxy-vitamin D3 receptor in the bursa of Fabricius of chicken |
| |
| Authors: | M Petrini F Bianchi A Dolfi M Lupetti |
| |
| Institution: | (1) Chair of Histology and Embryology, Faculty of Medicine, University of Pisa, Via Roma 55, I-56126 Pisa, (Italy);(2) Institute of Medical Clinic I, and Institute of Anatomy, University of Pisa, Via Roma 55, I-56126 Pisa, (Italy) |
| |
| Abstract: | The vitamin D3 metabolite 1,25(OH)2D3 is probably involved in B lymphocyte ontogeny. We therefore determined the distribution of the 1,25(OH)2D3 receptor in the bursa of Fabricius and spleen cells of 7-day-old chicks, by immunohistochemistry using a monoclonal antibody against the chick intestinal cell 1,25(OH)2D3 receptor. The bursa cells of young (7-day-old) chicks contained large amounts of receptor while the spleen cells did not. The bursa cells of older (35-day-old) chicks contained fewer receptors, but the number of receptors in the spleen increased. |
| |
| Keywords: | Vitamin D3 receptor dihydroxy-vitamin D3 bursa of Fabricius ontogeny of immune system B lymphocytes |
| 本文献已被 SpringerLink 等数据库收录！ |
|
