The dopamine autoreceptor agonist B-HT 920 markedly stimulates sexual behavior in male rats |
| |
Authors: | F. Ferrari G. Baggio V. Mangiafico |
| |
Affiliation: | (1) Institute of Pharmacology, University of Modena, Via G. Campi 287, I-41100 Modena, (Italy) |
| |
Abstract: | Summary B-HT 920, a selective agonist at dopamine (DA) autoreceptors, strongly increased the incidence of penile erections (PE) in male rats, an effect which was dose-related and antagonized by haloperidol. B-HT 920 at 100 and 200 g/kg i.p. significantly altered the copulatory pattern of sexually active male rats, reducing the number of mounts and intromissions as well as the latency to the first ejaculation, a stimulant effect which was confirmed in sluggish males at a dose of 100 g/kg. |
| |
Keywords: | B-HT 920 dopamine autoreceptors penile erections sexual behavior haloperidol rat |
本文献已被 SpringerLink 等数据库收录! |
|