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| 网状组织工程肌腱支架增强体的降解性能 | |
| 引用本文： | 蔡俊瑶,文添卉,邓丹,杨瑶斐,张佩华,陈明.网状组织工程肌腱支架增强体的降解性能[J].东华大学学报(自然科学版),2010,36(5). |
| 作者姓名： | 蔡俊瑶 文添卉 邓丹 杨瑶斐 张佩华 陈明 |
| 作者单位： | 1. 东华大学产业用纺织品教育部工程研究中心,上海,201620;东华大学纺织学院,上海,201620 2. 组织工程(上海)国家工程研究中心,上海,200235 3. 上海昌杰纺织品有限公司,上海,201620 |
| 基金项目： | 上海市教委科研创新项目，高等学校学科创新引智计划 |
| 摘 要： | 以聚乙醇酸(Polyglycolic Acid,PGA)纤维和聚乳酸(Polylactic Acid,PLA)纤维为原料,用编织的方法制成一种网状圆筒形组织工程肌腱支架的增强体,探讨不同孔径支架增强体在体外降解过程中的断裂现象、拉伸强力、断裂伸长、质量衰变特征.得出组织工程肌腱支架增强体的拉伸断裂规律,孔径大小对支架增强体在降解过程中的强力、伸长和质量衰减性能影响不大.将支架增强体与PGA纤维复合构成组织工程肌腱支架,并在其上种植皮肤成纤维细胞.试验结果显示孔径大小对组织工程肌腱支架的力学性质有较大影响,其生物相容性良好. |
| 关 键 词： | 网状 肌腱 支架 降解 性能 |
The Degradation Property of a Netty Structure Scaffold Reinforcement for Tendon Tissue Engineering |
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| CAI Jun-yao,WEN Tian-hui,DENG Dan,YANG Yao-fei,ZHANG Pei-hua,CHEN Ming.The Degradation Property of a Netty Structure Scaffold Reinforcement for Tendon Tissue Engineering[J].Journal of Donghua University,2010,36(5). | |
| Authors: | CAI Jun-yao WEN Tian-hui DENG Dan YANG Yao-fei ZHANG Pei-hua CHEN Ming |
| Institution: | CAI Jun-yao1a,1b,WEN Tian-hui1a,DENG Dan2,YANG Yao-fei 2,ZHANG Pei-hua1a,CHEN Ming3(a. Engineering Research Center of Technical Textiles,Ministry of Education,b. College of Textiles,1.Donghua University,Shanghai 201620,China,2. National Tissue Engineering Research , Development Center of China,Shanghai 200235,3. Shanghai Changjie Textiles Co Ltd,China) |
| Abstract: | A netty structure was made for reinforcing body of tendon scaffold tissue engineering, using polyglycolic acid(PGA) and polylactic acid(PLA) fibers. Each sample of different pore sizes was investigated on its form of tensile breaking, the change of strength and elongation as well as the mass decay characteristics during the degradation. The results showed the regular pattern of tensile rupture of the scaffold and indicated that the net size did not have much effect on the scaffold's strength, elongation and... |
| Keywords: | netty tendon scaffold degradation property |
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