Synthesis and Fluorescence Spectra of Triazolylcoumarin Fluorescent Dyes |
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Authors: | PENG Xian-fu LI Hong-qi |
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Affiliation: | Key Laboratory of Science & Technology of Eco-Textile,Ministry of Education,College of Chemistry and Chemical Engineering,Donghua University,Shanghai 201620,China |
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Abstract: | Much attention is devoted to fluorescent dyes especially those with potential in versatile applications. Reactions under "click" conditions between nonfluorescent 3 - azidocoumarins and terminal alkynes produced 3 -(1, 2, 3- triazol- 1 - yl)cournarins, a novel type of fluorescent dyes with intense fluorescence. The structures of the new coumarins were characterized by 1H NMR, MS, and IR spectra. Fluorescence spectra measurement demonstrated excellent fluorescence performance of the triazolylcoumarins and this click reaction is a promising candidate for bioconjugation and bioimaging applications since both azide and alkynes are quite inert to biological systems. |
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Keywords: | triazolylcoumarin1 fluorescent dye clickchemistry fluorescence spectra |
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