| 血小板相关抗体及膜糖蛋白检测在特发性血小板减少性紫癜患者诊断中的价值 |
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| 引用本文： | 王明弘,宋玉国,黄建文.血小板相关抗体及膜糖蛋白检测在特发性血小板减少性紫癜患者诊断中的价值[J].北华大学学报(自然科学版),2005,6(6):505-508. |
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| 作者姓名： | 王明弘 宋玉国 黄建文 |
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| 作者单位： | 北华大学,医学院,吉林,吉林,132013;北华大学,医学院,吉林,吉林,132013;北华大学,医学院,吉林,吉林,132013 |
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| 摘 要： | 探讨血小板相关抗体(PAIgG)和血小板膜糖蛋白GPIIb/Ⅲa表达在特发性血小板减少性紫癜(ITP)患者中的诊断价值.采用流式细胞术对ITP患者及各对照组的PAIgG,GPIIb/IIIa的表达情况进行测定.PAIg对ITP诊断具有较高的阳性率,同时,结合GPIIb /IIIa可提高ITP的诊断正确率;GPⅡb/Ⅲa可作为ITP患者疗效监测及判断预后的指标.
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| 关 键 词： | 血小板相关抗体 血小板减少性紫癜 特发性 |
| 文章编号： | 1009-4822（2005）06-0505-04 |
| 收稿时间： | 2005-09-18 |
| 修稿时间： | 2005年9月18日 |
Diagnosis Value of Platelet Associated Immunoglobulin G and Plateletmembrane Glycoprotein in Patients with Idiopathic Thrombocytopenic Purpura |
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| WANG Ming-hong,SONG Yu-guo,HUANG Jian-wen.Diagnosis Value of Platelet Associated Immunoglobulin G and Plateletmembrane Glycoprotein in Patients with Idiopathic Thrombocytopenic Purpura[J].Journal of Beihua University(Natural Science),2005,6(6):505-508. |
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| Authors: | WANG Ming-hong SONG Yu-guo HUANG Jian-wen |
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| Abstract: | The diagnosis value of platelet-associated immunoglobulin G(PAIgG) and platelet membrane glycoprotein GPIIb/IIIa in the patients with idiopathic thrombocytopenic purpura(ITP) were discussed.The expression of PAIgG and GPIIb/IIIa in patients with ITP and control groups were detected by using flow cytometry(FCM).In ITP patients,positive rate of PAIgG was higher,the correct diagnostic rate of ITP improved if PAIgG was combined with GPIIb/IIIa;GPIIb/IIIa can be considered as a marker for curing effect and judging prognosis. |
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| Keywords: | PAIgG Thrombocytopenic purpura Idiopathic |
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