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| 实验性草鱼胆中毒肾脏和肝脏损害的病理表现 | |
| 引用本文： | 何敏华,吴建新,钮荣祥,田昆仑,潘云,杨丽荣. 实验性草鱼胆中毒肾脏和肝脏损害的病理表现[J]. 大理学院学报：综合版, 2003, 2(1): 7-8 |
| 作者姓名： | 何敏华 吴建新 钮荣祥 田昆仑 潘云 杨丽荣 |
| 作者单位： | 1. 大理学院内科教研室,云南大理,671000 2. 大理学院生理病理生理教研室,云南大理,671000 3. 大理学院病理教研室,云南大理,671000 |
| 摘 要： | 目的：探讨实验性草鱼胆中毒的肝脏和肾脏病理变化，并探索药物治疗。方法：将大白鼠分为正常对照组、模型组和药物组，均胃饲鱼胆汁，48h后取肾脏和肝脏行病理检查。结果：草鱼胆中毒肾脏损害之病理表现为近曲小管上皮细胞变性、坏死，肾小球充血，肝细胞肿胀、变性、坏死；药物组和模型组的病理表现无明显差异。结论：草鱼胆中毒肾脏损害病理表现为急性肾小管坏死，肾小球无明显异常；具有抗氧化作用的药物康复新对其病理表现无明显影响。 |
| 关 键 词： | 实验性草鱼胆中毒 肾脏损害 肝脏损害 病理 |
| 文章编号： | CN53-1180(2003)01-0007-02 |
| 修稿时间： | 2002-08-28 |
The pathologicl changes of renal and hepatic damage on rats caused by grass carp bile |
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| HE Min-hua WUJian-xin NIURong-xiang et al. The pathologicl changes of renal and hepatic damage on rats caused by grass carp bile[J]. Journal of Dali University, 2003, 2(1): 7-8 | |
| Authors: | HE Min-hua WUJian-xin NIURong-xiang et al |
| Affiliation: | HE Min-hua 1 WUJian-xin 2 NIURong-xiang 2 et al |
| Abstract: | Objective:To study the pathological changes of renal and hepatic damage on rats caused by grass carp bile.Methods:To make the models of grass carp bile poisoning,take the kidey and liver for observation the pathological changes after48hours;Result:the pathological changes of kidney was the epithelial cells of proximal tubules swelling and necrotizing,the glomerulas fill with RBC in Bowmans space,hepatis cells was swelling and necrotizing;Conclusion:The renal damage by grass carp bile was mainly at the proximal tubules,the glomerule is normal generally. |
| Keywords: | Grass carp bile poisoning the damage of kidney and liver the pathological changes. |
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