基于格子Boltzmann方法的混沌微混合器仿真研究

微混合器是生物微流体芯片的重要组成部分，其通道特征尺寸一般在几十到几百微米，采用常规的流体有限元法很难获得令人满意的分析效果。本文采用格子Boltzmann方法对微混合器的特性进行模拟分析。通过对两种斜槽式底面混沌微混合器通道的流场速度进行计算，模拟痕量样品粒子在载体流中的整个分散混合过程，研究了样品粒子混合的标准偏差与混合距离的关系，发现其符合高斯曲线的规律。上述仿真研究结果与相关文献的实验数据非常一致。表明格子Boltzmann方法可以作为微流体混合器及微流体芯片设计中的一种有效的分析工具。

A Simulation Research for Chaotic Micro Mixer Based on Lattice Boltzmann Method

Micro mixer is an important part in bio-microfluidic chips. Since the cross section of the channel is of micrometers scale, the analysis would not get satisfactory result if we use general fluidic FEM. In this paper, a lattice Boltzmann method was used to simulate the characteristics of a micro mixer. Based on the computation of the flow speeds in the chaotic micro mixers with oblique grooves on the floors, the dispersive mixing processes of the trace sample particles in carrier flows were simulated, and the relation between mixing standard deviation and mixing passage length for the sample particles was investigated, which was found consistent with Gauss curve pattern. The simulation results agree well with the experiments data in the literature. Above results show that the lattice Boltzmann method could be used as a powerful tool for the researches of microfluidic mixers and microfluidic chips.